Much later, in about 1554, Theodosius of Bologna described4 a pale child could not move or sit, indeed hardly hold it head erect and which showed in the lower dorsal region both a gibbus and a marked lateral curvature Whether the child actually had rickets is not clear. Later, it is said that Bartholomaeus Reusner described in 1582 disease common among the inhabitants of Holland and Switzerland, characterized by bending of bones and cachexia of infants and an insatiable hunger Sprengel5 who reported this, gave the reference as de tabe infantum, Basel Unfortunately, no one has been able to find this article anywhere despite intensive searching over many years. A recent search of current electronic data bases were not helpful either.
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